Researcher position to research in the field of cryo-EM, independent use of the Titan-Krios microscope for a single-particle and tomography data collection, data processing, and manuscript preparation, at Department of Biochemistry and Biophysics, Stockholm University, Sweden
Deadline to Apply
May 30, 2021 (23: 59 GMT +1)
|No. of Position(s)||1|
|Salary||According to standard norms|
|Workplace||Department of Biochemistry and Biophysics|
|Contract Period||2 Years|
|Starting date||As per agreement|
Researchers are appointed primarily for purposes of research and must hold a Swedish doctoral degree or an equivalent degree from another country.
In the appointment process, special attention will be given to research skills, publication track record, and previous experience in difficult problem solving. Previous experience is required in the field of structural biology of bioenergetic complexes.
Responsibilities/ Job Description
The position involves research in the field of cryo-EM, independent use of the Titan-Krios microscope for a single-particle and tomography data collection, data processing, and manuscript preparation.
How to Apply?
- To apply, please click Apply Online button mentioned above
- The instructions for applicants are available at: How to apply for a position.
Please include the following information with your application
- Your contact details and personal data
- Your highest degree
- Your language skills
- Contact details for 2–3 references
and, in addition, please include the following documents
- Cover letter
- CV – degrees and other completed courses, work experience and a list of publications
- Research proposal (no more than 3 pages) describing:
– why you are interested in the field/project described in the advertisement
– why and how you wish to complete the project
– what makes you suitable for the project in question
- Copy of PhD diploma
- Letters of recommendation (no more than 3 files)
- Publications in support of your application (no more than 3 files).
About Research project
Structural biology of supercomplexes is a young and emerging field. However, the assignment of individual subunits and cofactors is challenging, and indeed multiple mistakes have been reported. A general architecture of the membrane photosystem complex I curving around Lhca9 and its position is flexible. The mobile subunit Lhca9 was shown to switch between the ‘tight’ and loose’ forms. Mechanistically, the structures informed that plastocyanin is not equally able to access its sites in photosystem I, suggesting its oxidation is a major rate-limiting step. The goal of the project is to isolate the mega-complex and investigate its substrate channeling by cryo-EM.
About Department of Biochemistry and Biophysics
SciLifeLab is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource hosted by Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University. The center also collaborates with several other universities.
Post expires at 8:59am on Monday May 31st, 2021 (GMT+9)