Researcher position in Biophysics, Sweden

    Researcher position in Biophysics, Sweden

    Researcher position to research in the field of cryo-EM, independent use of the Titan-Krios microscope for a single-particle and tomography data collection, data processing, and manuscript preparation, at Department of Biochemistry and Biophysics, Stockholm University, Sweden


    Deadline to Apply

    May 30, 2021 (23: 59 GMT +1)


    Overview

    PositionResearcher
    No. of Position(s)1
    Research AreaBiophysics
    SalaryAccording to standard norms
    WorkplaceDepartment of Biochemistry and Biophysics
    Stockholm University
    Sweden
    Contract Period2 Years
    Starting dateAs per agreement

    Qualifications

    Researchers are appointed primarily for purposes of research and must hold a Swedish doctoral degree or an equivalent degree from another country.

    Preference

    In the appointment process, special attention will be given to research skills, publication track record, and previous experience in difficult problem solving. Previous experience is required in the field of structural biology of bioenergetic complexes.

    Responsibilities/ Job Description

    The position involves research in the field of cryo-EM, independent use of the Titan-Krios microscope for a single-particle and tomography data collection, data processing, and manuscript preparation.

    How to Apply?

    • To apply, please click Apply Online button mentioned above
    • The instructions for applicants are available at: How to apply for a position.

    Documents Required

    Please include the following information with your application

    • Your contact details and personal data
    • Your highest degree
    • Your language skills
    • Contact details for 2–3 references

    and, in addition, please include the following documents

    • Cover letter
    • CV – degrees and other completed courses, work experience and a list of publications
    • Research proposal (no more than 3 pages) describing:
      – why you are interested in the field/project described in the advertisement
      – why and how you wish to complete the project
      – what makes you suitable for the project in question
    • Copy of PhD diploma
    • Letters of recommendation (no more than 3 files)
    • Publications in support of your application (no more than 3 files).

    About Research project

    Structural biology of supercomplexes is a young and emerging field. However, the assignment of individual subunits and cofactors is challenging, and indeed multiple mistakes have been reported. A general architecture of the membrane photosystem complex I curving around Lhca9 and its position is flexible. The mobile subunit Lhca9 was shown to switch between the ‘tight’ and loose’ forms. Mechanistically, the structures informed that plastocyanin is not equally able to access its sites in photosystem I, suggesting its oxidation is a major rate-limiting step. The goal of the project is to isolate the mega-complex and investigate its substrate channeling by cryo-EM.

    About Department of Biochemistry and Biophysics

    SciLifeLab is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource hosted by Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University. The center also collaborates with several other universities.

    Inquiries

    Alexey Amunts
    Email: amunts@scilifelab.se.

    Official advertisement

    Researcher in Biophysics

    Post expires at 8:59am on Monday May 31st, 2021 (GMT+9)

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