Postdoctoral Fellowship in Denmark – Molecular Microbial Ecology

    Postdoctoral Fellowship in Denmark - Molecular Microbial Ecology

    Postdoctoral Fellowship in Denmark is available to develop and deploy an innovative method to recover microbial cell harboring plasmid directly from the environment without relying on cultivation or selective markers, in Department of Biology, University of Copenhagen

    Postdoctoral Fellowship in Molecular Microbial Ecology


    Deadline to Apply

    June 13, 2021 23:59 (GMT +1 )


    Position

    Postdoctoral Fellowship

    No. of Position(s)

    1

    Research area

    • Molecular Microbial Ecology
    • Molecular Microbiology
    • Microbial Genetics
    • Biotechnology
    • Bacterial genetics
    • Bioinformatics
    • Structural biology

    Salary

    DKK 436.730 / Month

    Workplace

    Department of Biology
    Copenhagen N

    Contract period

    2 Years
    Starting date: September 1st 2021or as soon as possible thereafter

    Inquiries

    Joseph Nesme, PhD
    Email: joseph.nesme@bio.ku.dk  

    Qualifications

    • PhD in Molecular Microbiology, Microbial Genetics, Biotechnology or equivalent
    • We are a multicultural and multidisciplinary research team looking for a highly motivated, independent and ambitious researcher with an outstanding record of independent research in environmental microbiology and plasmid biology able to work as a teamplayer as well as independently, with an open communication style and a problem-solving attitude.

    Preference

    • Strong molecular microbiology and bacterial genetics background, with considerable experience working with bacterial culturing and state-of-the-art genetic manipulation techniques.
    • Basic bioinformatic skills (advanced skills are desired but not a requirement).
    • Experience with in-silico design of epitopes specific antibodies.
    • Previous experience with next-generation sequencing workflows, flow cytometry, and design of FACS analyses of bacterial communities will be considered an advantage.
    • Knowledge and research experience in structural biology and heterologous host protein production is highly desired.
    • Proficiency in English; excellent communication skills (written and spoken) is mandatory.
    • Experience teaching (BSc- and MSc-level courses) and mentoring students in the lab.
    • A publication record in relation to career stage.

    Responsibilities/Job Description

    The postdoc’s duties will include research as well as teaching. The post may also include performing other duties. Innovative ideas to reach the project objectives will be always welcomed and encouraged. 

    • In-silico design and testing of conjugative plasmid specific antibodies.
    • Development of high-throughput methodology for targeting and isolation of conjugative plasmids in from environmental matrices: soil, wastewater, freshwater.
    • Results dissemination at international conferences and peer-reviewed publications.

    How to Apply?

    The application, in English, must be submitted electronically by clicking APPLY NOW above

    Documents required

    • Motivated letter of application
    • Curriculum vitae
    • Complete List of publications
    • PhD and Master diploma or transcript in English
    • Separate reprints of 2 particularly relevant papers

    About Project

    This Postdoc position is associated with a fully funded project Catch me if you conjugate !” awarded by the Vellux Foundation. The aim of the project is to develop and deploy an innovative method to recover microbial cell harboring plasmid directly from the environment without relying on cultivation or selective markers.

    While plasmids are notoriously important in microbial ecology, bacterial adaptation and public health as vectors of antibiotic resistance, our current knowledge of the environmental plasmid and plasmid hosts pool is limited. This is due first because of the strong and understandable focus put on human and animal pathogens but also because of limited innovation on plasmid isolation methods. In this project, we will use immuno-targeting of the secreted conjugation machinery of different plasmid class, followed by flow-cytometry cell sorting and state-of-the-art sequencing methodologies.

    The project will blend together a highly diverse set of methods and techniques, both in the wet-lab and in silico. Specifically, we will use in silico design of antibodies targeting plasmid-specific epitopes; protein production and purification; fluorescence activated cell-sorting; high-throughput and long-reads sequencing using latest available platforms; complete closed microbial genome assembly and plasmid-host linkage at high-throughput.

    Note:

    • Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.
    • The starting salary is currently up to DKK 436.730 including annual supplement (+ pension up to DKK 74.681). Negotiation for salary supplement is possible. 

    Other Postdoctoral Positions

    Post expires at 8:59am on Monday June 14th, 2021 (GMT+9)