Postdoctoral fellow in Mucosal biology, at Institute of Biomedicine, University of Gothenburg, Sweden
Deadline to Apply
June 09, 2021 (23: 59 GMT +1)
|No. of Position(s)||1|
|Research Area||Mucosal biology|
|Salary||According to standard norms|
|Workplace||Institute of Biomedicine|
University of Gothenburg
|Contract Period||2 Years|
|Starting date||As per agreement|
An achieved doctoral degree is compulsory for a position as postdoctoral at the University of Gothenburg. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctoral aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.
The qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.
The profile we are looking for is a committed and responsible person with an ability to work independently and to be involved in the many collaborative studies performed. Applicants will be evaluated for relevant scientific and methodological skills as well as their personal engagement. The applicant must provide evidence of a PhD in a relevant research area with experience of working with animal models. Very good knowledge and experience in high resolution confocal microscopy and flow cytometry are considered strong merits and experience in single cell analysis, mass spectrometry, perfusion systems, histology and handling of clinical samples are highly valued. Knowledge in using a variety of methods including cell culture, molecular biology, and biochemistry is advantageous. Good skills in both written and spoken English are required.
Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.
Responsibilities/ Job Description
The work will include several different methods as ex vivo analysis of mucus on intestinal explants in a perfusion chamber using confocal microscopy. Expression of mRNA and protein in FACS sorted intestinal cells and different staining of tissue are also key methods in the project. Different murine colitis models, human biopsies from healthy and inflamed patients and cultured cells will be used. The research environment among the Mucin Biology Groups provides good opportunities to collaborate with, and learn from experts in a range of experimental methods. The applicant should also contribute to this environment with skills and knowledge. The candidate is expected to conduct the experimental research in an independent manner and extensively contribute to project planning and evaluation.
How to Apply?
To apply, please click the Apply Online button mentioned above
The application should contain:
- A cover letter giving a brief description of previous research experience, and what motivates you to apply for this position.
- A CV including a list of publications
- Proof of completed PhD
- Contact details of two references
About Research project
The gut is in many ways central to our perception of health and involves an intricate balance with the numerous microbes living in our intestine. The intestinal surface is covered by mucus as part of its protection and defects in the mucus system are associated with inflammatory disease. Mucus is produced and secreted by goblet cells that are found throughout the intestinal epithelium. Goblet cells are a heterogeneous cell population which we recently presented in Science (An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function) with various functions mostly not well understood. The objective is to continue this work by further investigating different human goblet cells and goblet cell and mucus alterations linked to inflammation in patients with IBD and in animal models. A particular focus will be to study a specific goblet cell type that is reduced in numbers in patients with ulcerative colitis and to determine the reason for their early detachment in disease.
About the Department
The University of Gothenburg tackles society’s challenges with diverse knowledge. 53 500 students and 6 500 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.
The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.
The Institute is composed of the following four departments:
- The Department of Infectious Diseases
- The Department of Microbiology and Immunology
- The Department of Medical Biochemistry and Cell Biology
- The Department of Laboratory Medicine
At present, the institute has about 360 employees and approximately 440 million SEK in total assets.
If you are interested in translational work in the area of mucosal biology and to learn new methods the “Mucus and colitis group”, led by Dr. Malin E. V. Johansson, at the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg can offer an exciting experience.
The research group is part of a world leading network of researchers (Mucin Biology Groups, http://www.medkem.gu.se/mucinbiology/) working together to understand the function of mucins and mucus protecting our different epithelial surfaces.
Information for International Applicants
Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:
Malin Johansson, Senior Lecturer, Associate professor
Post expires at 8:59am on Thursday June 10th, 2021 (GMT+9)