Postdoctoral researcher in Ubiquitin Signalling (biochemistry and mechanisms of stress and inflammation signalling) is available at DTU Bioengineering, Technical University of Denmark, Denmark.
Deadline to Apply
Jul 12, 2021 (23: 59 GMT +1)
|No. of Position(s)||1|
|Research Area||– Biochemistry|
– Molecular biology
|Salary||According to standard norms|
|Workplace||DTU Bioengineering, |
Technical University of Denmark, Denmark.
|Contract Period||2 Year|
|Starting date||Sept 01, 2021|
- PhD degree in biochemistry, molecular biology, or similar field
- Strong background in biochemistry, molecular biology, and experimental design / assay development
- Solid, demonstrated experience in protein biochemistry, including recombinant protein design, expression, and purification
- Demonstrated experience in molecular biology, including PCR and molecular cloning, gel electrophoresis, and DNA sequencing
- Demonstrated experience in in vitro enzymatic assays
- Experience with ubiquitin signalling, protein quality control, or cell stress
- Experience with analysis of cell signalling and multiprotein complexes (e.g. immunoprecipitation and pulldowns, western blotting, etc.)
- Experience with phage display technologies or nanobody discovery
- Experience with mammalian cell culture and cell biology
- Experience with flow cytometry
- Experience with genome editing (e.g. CRISPR/Cas9)
- Experience with mass spectrometry-based proteomics
- The successful candidate should thrive in a highly ambitious research group and will have demonstrated the ability to work independently and a documented track record of publication in internationally recognised peer-reviewed journals. Good communication skills in both written and spoken English are a requirement.
The assessment of the applicants will be made by Associate Professor Rune Busk Damgaard together with relevant project partners. Applications will be assessed on a rolling basis.
Responsibilities/ Job Description
- The postdoc will pioneer the development of new tools for deciphering atypical ubiquitin chain signalling, including M1-linked/linear chains, to understand how these ubiquitin modifications control cell signalling.
- The project will involve experimental laboratory work using nanobody discovery and phage display technologies, molecular cloning, protein biochemistry, recombinant protein expression, in vitro assays, molecular cell biology, and cell culture systems to develop new techniques and tools to study the function of the enigmatic atypical ubiquitin modifications in cells. The project may also include cutting-edge mass spectrometry-based proteomics analyses performed in collaboration with the DTU Proteomics Core.
How to Apply?
To apply, please open the link “Apply online”, fill in the online application form, and attach all your materials in English in one PDF file
Applications must be submitted as a single PDF file containing all materials to be given consideration. The file must include:
- Application (cover letter)
- List of publications
- Academic diplomas (PhD, or MSc diploma if PhD degree has not been conferred)
- Names and contact details for two academic references
The Ubiquitin Signalling and Inflammation Lab offers a highly ambitious, exciting, encouraging, and dynamic work environment. Together, we design and execute experiments that lead to discovery of new signalling mechanisms involved in development of inflammatory disease and cancer. We work together in a young and fun team. We grow together as scientists to tackle important, fundamental research questions
The Ubiquitin Signalling and Inflammation lab is part of the Department of Biotechnology and Biomedicine, Technical University of Denmark. The department is highly interdisciplinary and a leading department within life sciences in Denmark, covering both fundamental, technological, and applied aspects of biomedical research. The successful candidate will join a recently started lab with excellent funding and support from Novo Nordisk Foundation, Lundbeck Foundation, and DTU. The candidate will benefit from a thriving international and collaborative community and state-of-the-art facilities with access to cutting-edge technologies and equipment
- If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark
- All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply
Post expires at 8:59am on Tuesday July 13th, 2021 (GMT+9)