Postdoc Fellowship in the Metabolic Regulation of Chromatin States in Early Development is available at The Danish Stem Cell Center (DanStem) at Faculty of Health & Medical Sciences at the University of Copenhagen, Denmark (Life Sciences, Metabolomics and Biology Jobs)
Deadline to Apply
May 14, 2021 (23: 59 GMT +1)
|No. of Position(s)||1|
|Research Area||– Life Sciences|
|Salary||~ 34,622 DKK / Month|
|Workplace||The Danish Stem Cell Center (DanStem)|
Faculty of Health & Medical Sciences
University of Copenhagen
|Contract Period||2 Years|
|Starting date||July 15, 2021|
- A PhD degree in life sciences
- We are seeking an enthusiastic and outstanding post-doctoral candidate with a strong background in either mouse and stem cell biology and/or biochemistry and metabolomics.
- Documented hands on experience in stem cell biology and/or metabolomics
- Good record of peer-reviewed scientific publications
- Strong background in mouse genetics, cell biology and/or epigenetics.
- Alternatively candidates with a background in metabolomics applied to mammalian models are also encouraged to apply.
- Previous experience in metabolomics, bioinformatics, next-generation sequencing, mouse embryology and/or stem cell culture are considered an advantage.
- Excellent English skills written and spoken
- A solution-oriented, organizational and positive mindset is required.
- The ability to work in a highly collaborative environment both independently and as part of the team is essential.
Responsibilities/ Job Description
The candidate will implement cutting-edge proteomic and metabolomic assays unravel how metabolism regulates chromatin states in mouse and human stem cells.
By using functional assays in combination with live imaging and ultra-sensitive chromatin mapping and metabolomic techniques the candidate will get at the underlying principles of epi-metabolic regulation.
How to Apply?
Your online application must be submitted in English, by clicking on “Apply online” above.
- Motivation letter (It should describe your long-term research vision, the reason for applying to be part of our team and why you think you are the right candidate to fill this position)
- Curriculum vitae incl. education, experience, previous employments, language skills and other relevant skills
- List of three references (full address, incl. email and phone number)
- List of publications
- Copy of diplomas/degree certificate(s)
About Research project
- A postdoctoral position is available in the group of Jan Żylicz at DanStem.
- The team studies fundamental mechanisms of early mouse development and stem cell biology.
- The Żylicz group wants to understand how metabolic and epigenetic mechanisms cooperate to regulate transcription during early development.
- In particular, the team is interested in how metabolism regulates histone modifiers, and how these in turn affect lineage choice and embryo growth at around the time of implantation.
- To achieve this, the group utilizes both in vivo mouse models as well as in vitro stem cell culture systems and state-of the-art ultrasensitive transcriptomic, epigenomic and metabolomic techniques.
- This project will combine these methods with biochemical and mechanistic analysis in mouse and human stem cell models.
About the Department
The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem has been established as a result of a series of international recruitments coupled with internationally recognized research groups focused on insulin producing beta cells and cancer research already located at the University of Copenhagen. DanStem addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new strategies and targets for the development of new therapies for cancer and chronic diseases such as diabetes and liver failure. Find more information about the Center at https://danstem.ku.dk/
Associate Professor Jan Zylicz
Post expires at 8:59am on Saturday May 15th, 2021 (GMT+9)