Postdoc Position in Computational stem cell biology at BRIC is available at the Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (Stem Cell Research, Computational Biology and Bioinformatics Jobs)
Deadline to Apply
May 31, 2021 (23: 59 GMT +1)
|No. of Position(s)||Open|
|Research Area||– Bioinformatics |
– computational biology
|Salary||~34,600 DKK/ month|
|Workplace||Biotech Research & Innovation Centre|
Faculty of Health and Medical Sciences,
University of Copenhagen,
|Contract Period||3 Years|
|Starting date||Aug 01, 2021|
Essential experience and skills:
- You are a highly self-motivated and ambitious scientist
- You have a PhD in Bioinformatics or computational biology
- You have an excellent track record with at least 1 peer reviewed first author paper in a high-impact journal
- You have a strong background in bioinformatics and computational biology, and it will be regarded as an advantage if you have experience with analysis of single cell data
- You have the ability to independently envision, plan and execute a research project
- You have excellent technical skills
- You have excellent English skills written and spoken
Responsibilities/ Job Description
The recruited postdoc will work closely with other members of our highly international team to address the role of specific cell populations in colonic tissue regeneration as well as signalling pathways involved in tissue repair using state-of-the-art methodologies including single-cell RNA sequencing, fate mapping, organoid models and genetic mouse models.
We are looking for an ambitious postdoctoral candidate with a strong background in bioinformatics/computational biology, who is interested in establishing a mathematical model describing cell fate during tissue regeneration in the intestinal epithelium. In the Jensen lab you will be an integral part of a small sub-team with clearly defined individual objectives and research goals. Using state-of-the-art cell biology tools, genetic mouse models and genome engineering, you will help us develop a framework based on computational analysis of single cell RNA sequencing data and quantitative fate mapping data. Depending on your interest this could also include turning the framework into an open source tool/package The work will bridge human and mouse regeneration, and help determine which key regulatory mechanisms control changes in cell fate decisions
How to Apply?
Your online application must be submitted in English by clicking ‘Apply Online’ button mentioned above.
Your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education, work/research experience, language skills and other skills relevant for the position.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications.
About Research project
The epithelial tissues along our entire body have to establish an important barrier to protect from the hostile environment. This is achieved via the balanced production of differentiated offspring from resident stem cell populations. Dysregulation of this fine balance lies at the root of diseases such as ulceration and cancer. In the Jensen lab we use a combination of animal models and patient derived material to address fundamental questions related to the formation, maintenance and regeneration of epithelial tissues. Here we use a range of interdisciplinary approaches and technologies to identify and characterize candidate genes regulating cell fate changes (Wong et al., 2012, Nature Cell Biology; Fordham et al., 2013, Cell Stem Cell; Page et al., 2013; Yui et al., 2018, Cell Stem Cell; Cell Stem Cell; Guiu et al., 2019, Nature; Andersen et al., 2019, Nature Cell Biology).
Place of Employment
The place of employment is at BRIC, Biocenter, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities including a single cell core and a CRIPSR platform facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD and our own https://www.bric.ku.dk/phd-and-postdoc-programme/postdoc-career-programme/. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://eu-life.eu/. The Jensen group is also affiliated with DanStem
- Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
- The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
- Interviews are expected to be held in last part of June
Professor Kim Jensen
Post expires at 8:59am on Tuesday June 1st, 2021 (GMT+9)