DTU PhD Position in Bioengineering – Human milk oligosaccharides’ impact on maturation of the gut microbiota

    DTU PhD Position in Bioengineering - Human milk oligosaccharides’ impact on maturation of the gut microbiota

    PhD scholarship in the project “Human milk oligosaccharides’ impact on maturation of the gut microbiota” is available at DTU Bioengineering, Technical University of Denmark, Denmark


    Deadline to Apply

    June 25, 2021 (23: 59 GMT +1)


    Overview

    PositionPhD Position
    No. of Position(s)1
    Research Area– Bioinformatics
    – Biochemistry
    – Microbiology
    Scholarship“According to standard norms”
    WorkplaceDTU Bioengineering,
    Technical University of Denmark, Denmark
    Contract Period3 Years
    Starting dateOct 01, 2021

    Qualifications

    • A two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree.
      Ideal candidates:
    • Outstanding academic record with a strong background in bioinformatics with a biochemistry or microbiology foundation.
    • Strong computational skills and interest in programming and statistics relevant to advanced bioinformatics analyses
    • Experimental skills in microbiology, biochemical protein characterization and transcriptomic analyses are great advantages
      This position ideal for you if:
    • You are hardworking, talented and highly motivated
    • Independent and creative
    • Appreciate working on a cross-disciplinary collaborative project with potential for major discoveries
    • Enjoy good collaborations, and a relaxed informal and international atmosphere in our groups.
    • Have excellent oral and written communication skills in English

    Assessment

    The assessment of candidates will be made by Prof. Maher Abou Hachem and Dr. Michael Jakob Pichler.

    Responsibilities

    Your tasks will be to:

    • Analyse and discover the genetic potential of human milk oligosaccharide utilisation in available large metagenomic datasets from the human gut microbiota (collaboration with Assoc. Prof. Manimozhiyan Arumugam)
    • Generate and analyse metagenomic and metatranscriptomic data from specific bacterial groups isolated in the project
    • Perform an in vivo colonisation experiment in germfree mice and analyse changes in the gut microbiota (e.g. metagenome, microbiota metabolite profiles) under specific stimuli
    • In vitro microbiological growth experiments of anaerobic bacterial isolates from the HGM and biochemical characterisation of HMO utilisation enzymes and proteins 

    How to Apply?

    To apply, please open the link “Apply online”, fill out the online application form, and attach all your materials in English in one PDF file.

    Documents Required

    Applications must be submitted as one PDF file containing all materials to be given consideration. The file must include:

    • A letter motivating the application (cover letter)
    • Curriculum vitae
    • Grade transcripts and BSc/MSc diploma
    • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)
    • List of publications if any
    • References

    About the project/department

    A major focus of this group, headed by Prof. Maher Abou Hachem, is to perform impactful and pioneering work on understanding the molecular basis of glycan utilisation the human gut microbiota to develop mechanism-based interventions for editing the gut microbial community to promote health and combat disease.

    The PhD research project is a collaboration with the groups of Assoc. Prof. Manimozhiyan Arumugam (University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research) and Assoc. Prof. Eric C. Martens (University of Michigan Medical School, Michigan, USA). The project’s goal is to bring insight into the role of human milk oligosaccharides (HMOs) in the maturation of the human gut microbiota, which is an important determinant of human health.

    Note

    • All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
    • If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

    Inquiries

    Maher Abou Hachem,
    Tel.: +45 4525 2732,
    E-mail: maha@bio.dtu.dk.

    Official advertisement

    PhD scholarship in the project “Human milk oligosaccharides’ impact on maturation of the gut microbiota”

    Post expires at 9:26pm on Saturday June 26th, 2021 (GMT+9)

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