Postdoc Position in the field of intracellular calcium signaling in mammary epithelial and breast cancer cells is available at the Department of Biomedicine, Faculty of Health, Aarhus University, Denmark (Job for Pharmacology, Biotechnology, Cell Biology, Cancer Cell Study)
Deadline to Apply
May 05, 2021 (23: 59 GMT +1)
|No. of Position(s)||1|
|Research Area||– Epithelial Cell Biology|
– Breast Cancer or Pharmacology.
|Salary||DKK 486,969.17 ~ 512,713.62 / Annum|
|Workplace||Department of Biomedicine|
Høegh-Guldbergs Gade 10,
DK-8000 Aarhus C, Denmark
|Contract Period||48 month|
|Starting date||Nov 01, 2021 or ASAP|
- PhD level, preferably within one or more of the following areas Epithelial Cell Biology, Breast Cancer or Pharmacology.
- As a person, you are ambitious, take ownership and possess good communication and interpersonal skills.
- We expect you to be fluent in oral and written English.
Responsibilities/ Job Description
As Postdoc in the Calcium Signalling Laboratory your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.
Your main tasks will consist of:
- Independent research of high international quality, including publication, in the field of calcium signalling.
- Data analysis, e.g., development of MATLAB algorithms to analyze large time series data.
- Culture of breast cancer cell lines, mammary epithelial cell lines, co-cultures and culture of primary cells.
- Intracellular calcium imaging using genetically encoded calcium sensors and calcium sensitive dyes.
- Pharmacological assays
- High-throughput pharmacological screens and high-content imaging.
- Gene expression modification, including production of lentiviral vectors for protein expression or shRNA knockdown, as well as gene knockdown via siRNA. Generation and assessment of clonal cell lines.
- Assessment of gene and protein expression e.g., qPCR, western blotting, and immunofluorescence staining
- Molecular cloning: basic experience in plasmid generation through restriction cloning, shRNA primer design and insertion in lenti-viral backbone vector, growth and isolation of plasmids in bacteria.
How to Apply?
To apply, please click APPLY ONLINE button mentioned above.
Your application must include the following:
- Motivated application
- Curriculum Vitae
- A list of publications
- A teaching portfolio. We refer to Guideline on the use of teaching portfolios
- A maximum of five of the publications of greatest relevance to the job may be submitted
- Template for applicant – postdoc must be completed and uploaded under ‘Extra documents’
- Strategic research plan can be uploaded
- Coauthor statement(s) can be uploaded
- References/recommendations can be uploaded separately in the e-recruitment system
About Research project
How thousands to billions of cells are produced and arranged in space and time to execute a defined task at the cell level and cooperatively achieve a biological outcome at the organ level, remains an important question at the core of biomedical science. When an organ malfunctions, medical interventions typically focus on restoring function, where possible, or repairing or replacing damaged tissue.
To optimally achieve these goals, however, we must first understand how the organ is formed, how it may regenerate and how it fundamentally works. The lack of models and methods to visualize how cells in complex environments sense, decode and respond to developmental and physiological cues has limited progress in this area. Using volumetric calcium imaging and computational platforms for image analysis, we are able to observe and quantify signal-response relationships in individual mammary epithelial cells deep within the living gland. The laboratory is using this approach to understand how the mammary gland and mammary tumours develop.
About the Department
We offer a vibrant international research environment where English is the preferred language in the laboratory, at meetings and at seminars. The Department employs some 450 people and covers a range of research areas within Biomedicine. We contribute to the Bachelor’s degree programs in medicine, molecular medicine, odontology and the Master’s degree programs in biomedical engineering and medical chemistry. Our infrastructure is well developed with modern laboratories, core and animal facilities. You will work either in the brand new ‘Skou Building’ or similar as we are in the process of modernizing our old facilities. You can read more about the department here and about the faculty here.
- We refer to the faculty’s Guidelines for applicants.
- The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.
- All interested candidates are encouraged to apply, regardless of their personal background.
- We expect to conduct interviews May 2021.
- Questions about application and process?
HE Administrative Centre – Health HR
Letter of reference
If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.
Associate Professor Felicity Davis
Post expires at 8:59am on Thursday May 6th, 2021 (GMT+9)